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1

Multicopy plasmids potentiate the evolution of antibiotic resistance in bacteria

San Millan, Alvaro, Escudero, Jose Antonio, Gifford, Danna R., Mazel, Didier, MacLean, R. Craig

Journal:

Nature Ecology & Evolution

Year:

2016

Language:

english

File:

PDF, 452 KB

english, 2016

2

Microbial Evolution: Towards Resolving the Plasmid Paradox

MacLean, R. Craig, San Millan, Alvaro

Journal:

Current Biology

Year:

2015

Language:

english

File:

PDF, 402 KB

english, 2015

3

Evaluating the effect of horizontal transmission on the stability of plasmids under different selection regimes

Peña-Miller, Rafael, Rodríguez-González, Rogelio, MacLean, R Craig, San Millan, Alvaro

Journal:

Mobile Genetic Elements

Year:

2015

Language:

english

File:

PDF, 630 KB

english, 2015

4

Interactions between horizontally acquired genes create a fitness cost in Pseudomonas aeruginosa

Millan, Alvaro San, Toll-Riera, Macarena, Qi, Qin, MacLean, R. Craig

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 973 KB

english, 2015

5

The evolution of antibiotic resistance

MacLean, R. Craig, San Millan, Alvaro

Journal:

Year:

2019

File:

PDF, 914 KB

2019

6

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Escudero, Jose Antonio, MacLean, R Craig, San Millan, Alvaro

Journal:

Journal of Visualized Experiments

Year:

2018

Language:

english

File:

PDF, 266 KB

english, 2018

7

Sequencing of plasmids pAMBL1 and pAMBL2 from Pseudomonas aeruginosa reveals a bla VIM-1 amplification causing high-level carbapenem resistance

San Millan, Alvaro, Toll-Riera, Macarena, Escudero, Jose Antonio, Cantón, Rafael, Coque, Teresa M., MacLean, R. Craig

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2015

Language:

english

File:

PDF, 337 KB

english, 2015

8

Fitness Costs of Plasmids: a Limit to Plasmid Transmission

San Millan, Alvaro, MacLean, R. Craig

Journal:

Microbiology Spectrum

Year:

2017

Language:

english

File:

PDF, 848 KB

english, 2017

9

Cooperation, competition and antibiotic resistance in bacterial colonies

Frost, Isabel, Smith, William P. J., Mitri, Sara, Millan, Alvaro San, Davit, Yohan, Osborne, James M., Pitt-Francis, Joe M., MacLean, R. Craig, Foster, Kevin R.

Journal:

The ISME Journal

Year:

2018

Language:

english

File:

PDF, 4.75 MB

english, 2018

10

PCR-Based Analysis of ColE1 Plasmids in Clinical Isolates and Metagenomic Samples Reveals Their Importance as Gene Capture Platforms

Ares-Arroyo, Manuel, Bernabe-Balas, Cristina, Santos-Lopez, Alfonso, Baquero, Maria R., Prasad, Kashi N., Cid, Dolores, Martin-Espada, Carmen, San Millan, Alvaro, Gonzalez-Zorn, Bruno

Journal:

Frontiers in Microbiology

Year:

2018

Language:

english

File:

PDF, 2.74 MB

english, 2018

11

Culturable aerobic and facultative bacteria from the gut of the polyphagic dung beetle Thorectes lusitanicus

Hernández, Noemi, Escudero, José A., Millán, Álvaro San, González-Zorn, Bruno, Lobo, Jorge M., Verdú, José R., Suárez, Mónica

Journal:

Year:

2015

Language:

english

File:

PDF, 409 KB

english, 2015

12

Small-Plasmid-Mediated Antibiotic Resistance Is Enhanced by Increases in Plasmid Copy Number and Bacterial Fitness

San Millan, Alvaro, Santos-Lopez, Alfonso, Ortega-Huedo, Rafael, Bernabe-Balas, Cristina, Kennedy, Sean P., Gonzalez-Zorn, Bruno

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 947 KB

english, 2015

13

The evolution of antibiotic resistance

MacLean, R. Craig, San Millan, Alvaro

Journal:

Year:

2019

Language:

english

File:

PDF, 914 KB

english, 2019

14

Positive epistasis between co-infecting plasmids promotes plasmid survival in bacterial populations

San Millan, Alvaro, Heilbron, Karl, MacLean, R Craig

Journal:

The ISME Journal

Year:

2014

Language:

english

File:

PDF, 1.74 MB

english, 2014

15

A naturally occurring SNP in plasmid pB1000 produces a reversible increase in antibiotic resistance

Santos-Lopez, Alfonso, Bernabe-Balas, Cristina, Ares-Arroyo, Manuel, Ortega-Huedo, Rafael, Hoefer, Andreas, San Millan, Alvaro, Gonzalez-Zorn, Bruno

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 839 KB

english, 2016

16

The Genomic Basis of Evolutionary Innovation in Pseudomonas aeruginosa

Toll-Riera, Macarena, San Millan, Alvaro, Wagner, Andreas, MacLean, R. Craig, Guttman, David S.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

17

Integrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1

San Millan, Alvaro, Toll-Riera, Macarena, Qi, Qin, Betts, Alex, Hopkinson, Richard J., McCullagh, James, MacLean, R. Craig

Journal:

The ISME Journal

Year:

2018

Language:

english

File:

PDF, 1.77 MB

english, 2018

18

Evolution of Plasmid-Mediated Antibiotic Resistance in the Clinical Context

San Millan, Alvaro

Journal:

Trends in Microbiology

Year:

2018

Language:

english

File:

PDF, 1.37 MB

english, 2018

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